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Q: I've heard about a new type of artery disease that affects women. What is it?

Ask Our Expert About Hidden Heart Disease

Q: I've heard about a new type of artery disease that affects women. What is it?

A: In this condition, cholesterol plaque spreads evenly within the walls of the arteries rather than forming major blockages. The condition has been called by different names-hidden heart disease, microvascular syndrome, endothelial dysfunction, syndrome X. It may affect as many as 3 million American women.

Q: What are the symptoms?

A: The main symptom is chest pain or discomfort. But the condition does not show up on an angiogram-the most common test for coronary disease-because since there are no actual blockages, the arteries look clear on the X-ray.

Q: Why is hidden heart disease dangerous?

A: It causes narrowing of the arteries and reduced blood flow to the heart. Healthy arteries are able to dilate when the heart muscle needs more oxygen-laden blood. In a person with hidden heart disease, the arteries don’t respond as they should. That raises the risk for heart attack and stroke-yet the patient isn't aware of her increased risk because her arteries appear fine in the angiogram.

Q: How was hidden heart disease discovered?

A: We've known for some time that this condition exists, but didn't realize how common it is until the findings of a major study were published recently. The study, called WISE (Women's Ischemia Syndrome Evaluation), included 936 women who had symptoms that led their doctors to order angiograms. Only a third of the women had obvious blockages. But of those without blockages, more than half turned out to have artery abnormalities such as the inability to dilate.

Q: How do you test for hidden heart disease?

A: We don't know yet what the most effective tests will be. The researchers in the study used a type of stress test to measure coronary flow velocity-how fast and well the blood flows in response to a drug that prompts the artery to dilate. This is not currently considered a routine test.

Q: Who is at risk for hidden heart disease?

A: The risk factors are very similar to those for other types of coronary disease. They include smoking, obesity, high cholesterol, high blood pressure (hypertension), diabetes, sedentary lifestyle and a family history of heart disease.

Q: How is hidden heart disease treated?

A: Researchers will be studying the best treatments, but we know that with any type of heart disease, it is vital to address your risk factors. That means quitting smoking, maintaining a healthy weight, staying physically active and keeping cholesterol, blood pressure and blood glucose under control.

Q: So if I have chest pain, I should take it seriously?

A: Definitely! You should take any symptom seriously that could indicate a heart attack. Women are more likely than men to have more atypical symptoms such as: extreme fatigue, indigestion, chest discomfort with lightheadedness, fainting, sweating or shortness of breath. If you have any of these symptoms, call 9-1-1 immediately and chew an aspirin tablet. Even if the symptoms turn out to be something else, it's better to be safe than sorry, and in a heart attack every minute counts.

Q: And if I have an angiogram and it turns out clear, I should talk to my doctor about hidden heart disease?

A: Yes. Even if you have no symptoms, a "heart-to-heart" talk with your doctor is a wise idea for every woman. Together, you can assess your risk and decide on the best strategy for keeping yourself healthy and heart-disease free.

Want to find a family doctor specially-trained in caring for a woman's heart? Heart Help for Women doctors are educated to recognize a woman's unique risk and symptoms for heart disease. Call 610-402-CARE to find a doctor.

This page last updated 2/12/08 04:08 PM
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Lehigh Valley Hospital has campuses in Allentown and Bethlehem, Pa. and serves the Pennsylvania communities of Easton, Doylestown, Quakertown, Hazelton, Lehighton, Perkasie, Pottstown, Pottsville, Reading, Scranton, Wilkes Barre, Stroudsburg, and the Poconos and also Phillipsburg and Flemington, N.J., and western New Jersey. You don't have to travel to Philadelphia or New York for quality health care.

 
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